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New Products Posted to GenomeWeb: MGI, Tecan, Qiagen, More

MGI HotMps High-Throughput Sequencing Kit

BGI Group affiliate MGI has launched new commercial sequencing chemistry called HotMps for its DnbSeq-G400 sequencer. Built upon the combinatorial Probe Anchor Synthesis technology proprietary to MGI, HotMps can achieve low error rates, low duplication rates, and low index hopping while being compatible with commonly used library preparation methods, according to MGI. The company said HotMps will be available in certain countries from April 2022. Early-access collaborators have successfully used the chemistry on applications such as whole-genome sequencing, whole-exome sequencing, transcriptome sequencing, and metagenome sequencing, the company added.

Tecan MagicPrep NGS

Tecan has launched the MagicPrep NGS, a fully automated benchtop library preparation system for next-generation sequencing. With liquid handling technology, all-inclusive reagent kits, and an intuitive user interface, the instrument can be set up within 10 minutes and generates eight sequencer-ready libraries with high success rates, the company claimed. The instrument can prepare DNA or mRNA libraries and is compatible with Illumina sequencing platforms.

Qiagen Biomedical Knowledge Base

Qiagen Digital Insights, the bioinformatics division of Qiagen, has introduced Biomedical Knowledge Base, a collection of manually curated data that lists structured biomedical relationships between elements including genes, diseases, functions, targets, drugs, and chemicals to power graph analysis, artificial intelligence, machine learning, and other drug discovery applications. Qiagen Biomedical Knowledge Base, which will initially be available in North America, Europe, Japan, and Australia, is the company's first product targeting data scientists.

For more new products and services, please visit the New Products page on our website.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.