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New Products Posted to GenomeWeb: Illumina, Yourgene Health, Meridian Bioscience

Illumina TruSight Oncology 500 HRD Assay

Illumina has launched the TruSight Oncology 500 HRD assay, a next-generation sequencing-based clinical assay for homologous recombination deficiency status. The test, codeveloped with Merck and based on validated HRD technology from Myriad Genetics, analyzes more than 500 genes, including those relevant to HRD status. HRD signatures occur when cells are unable to effectively repair double-strand breaks in DNA. Illumina expects to ship the kit in August; however, the test will not be available in the US and Japan.

Yourgene Health LightBench Detect

Yourgene Health has launched LightBench Detect, an electrophoresis instrument to automate DNA size selection and enrichment from samples stored in EDTA blood collection tubes for use in liquid biopsy assays, including noninvasive prenatal testing. According to the firm, LightBench Detect helps NIPT providers to reduce no-call rates by enriching cell-free DNA of fetal origin, which is typically under 150 bp in length. The instrument, which is part of Yourgene's Ranger technology portfolio, also enables fragment length analysis and fluorescence assays for quality control.

Meridian Bioscience Lyo-Ready Direct DNA qPCR Stool Mix, Lyo-Ready Direct RNA/DNA qPCR Stool Mix

Meridian Bioscience has launched two new sample-specific master mixes, Lyo-Ready Direct DNA qPCR Stool Mix and Lyo-Ready Direct RNA/DNA qPCR Stool Mix, to improve the molecular detection of DNA and RNA from crude fecal specimens and to allow room temperature stabilization of diagnostic assays. Detection of DNA or RNA from stool can be difficult because stool contains many PCR inhibitors including bile salts, polysaccharides, and catabolic substances. Meridian's two mixes remove the need for nucleic acid extraction or lengthy component optimization and can be used in liquid or lyophilized format when ambient temperature assay stabilization is needed.

For more new products and services, please visit the New Products page on our website.

The Scan

ChatGPT Does As Well As Humans Answering Genetics Questions, Study Finds

Researchers in the European Journal of Human Genetics had ChatGPT answer genetics-related questions, finding it was about 68 percent accurate, but sometimes gave different answers to the same question.

Sequencing Analysis Examines Gene Regulatory Networks of Honeybee Soldier, Forager Brains

Researchers in Nature Ecology & Evolution find gene regulatory network differences between soldiers and foragers, suggesting bees can take on either role.

Analysis of Ashkenazi Jewish Cohort Uncovers New Genetic Loci Linked to Alzheimer's Disease

The study in Alzheimer's & Dementia highlighted known genes, but also novel ones with biological ties to Alzheimer's disease.

Tara Pacific Expedition Project Team Finds High Diversity Within Coral Reef Microbiome

In papers appearing in Nature Communications and elsewhere, the team reports on findings from the two-year excursion examining coral reefs.