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New Products Posted to GenomeWeb: Illumina, NanoString Technologies, New England Biolabs, More

This column was posted on Nov. 13 but not included in GenomeWeb's bulletin that day due to a technical issue.

Illumina NextSeq 1000, P3 Reagent Kit for NextSeq 2000

Illumina's mid-throughput NextSeq 1000 sequencing system is now commercially available. The instrument offers 400 million reads per run and is more affordable than the NextSeq 2000. It has onboard informatics for rapid secondary analysis.

Illumina has also launched the P3 reagent kit for its NextSeq 2000 sequencing system. The high-output flow cell offers 1.1 billion reads per run, more than three times more than previously available on Illumina's mid-throughput systems. The kit will be available in four configurations: the 100-cycle kit delivers 110 Gb per run; the 200-cycle kit, 220 Gb; and the 300-cycle kit, 330 Gb. A 50-cycle kit is also available for infectious disease, small RNA, and spatial transcriptomics applications.


NanoString Technologies GeoMx DSP Protein Assays for NGS

NanoString Technologies has launched its GeoMx DSP Protein assays for next-generation sequencing readout.

The assays expand the multiplex detection capabilities of GeoMx digital spatial profiling from tens to hundreds of proteins and include more than 50 targets for immuno-oncology applications. The assays also provide complementary protein content for the GeoMx Cancer Transcriptome Atlas panel.

The firm said it has tested performance on both formalin-fixed, paraffin-embedded and fresh frozen tissue samples.

The products are available immediately through NanoString's technology access program.


New England Biolabs: Monarch HMW DNA Extraction Kits

New England Biolabs has released two high molecular weight (HMW) DNA extraction kits. Both the Monarch HMW DNA Extraction Kit for Cells & Blood and the Monarch HMW DNA Extraction Kit for Tissue utilize a novel glass bead-based technology that allows for more efficient and cost-effective extraction. They can extract DNA up to several megabases in size from cells, blood, tissue, or bacteria, with workflows that range from 30 minutes to 90 minutes in duration.

The extracted DNA can be used in downstream applications such as long-read sequencing, optical mapping, and linked-read genome assembly. The new kits complement the company's Monarch Genomics DNA Purification Kit and can be used alongside its NEBNext Companion Module for Oxford Nanopore Technologies Ligation Sequencing kit.


For more new products and services, please visit the New Products page on our website.

The Scan

Germline-Targeting HIV Vaccine Shows Promise in Phase I Trial

A National Institutes of Health-led team reports in Science that a broadly neutralizing antibody HIV vaccine induced bnAb precursors in 97 percent of those given the vaccine.

Study Uncovers Genetic Mutation in Childhood Glaucoma

A study in the Journal of Clinical Investigation ties a heterozygous missense variant in thrombospondin 1 to childhood glaucoma.

Gene Co-Expression Database for Humans, Model Organisms Gets Update

GeneFriends has been updated to include gene and transcript co-expression networks based on RNA-seq data from 46,475 human and 34,322 mouse samples, a new paper in Nucleic Acids Research says.

New Study Investigates Genomics of Fanconi Anemia Repair Pathway in Cancer

A Rockefeller University team reports in Nature that FA repair deficiency leads to structural variants that can contribute to genomic instability.