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New Products Posted to GenomeWeb: DNAStar, Twist Bioscience, Biotia, GeneMatters, More

DNAStar Lasergene 17.2 Software

DNAStar has released Lasergene 17.2 software for DNA, RNA, and protein sequencing assembly and analysis. In the latest release, DNAStar has fully integrated the SeqMan NGen application into SeqMan Ultra, greatly improving the workflow for both Sanger and next-generation sequencing analysis.

Users performing sequence assemblies can now go from project setup to finished assembly in one application. For users working with Sanger sequencing data, the new software offers improvements such as the ability to preview and trim trace data prior to assembly; better access to a built-in vector trimming database; and the ability to easily export an image of the assembly for collaboration or publication.

For those doing NGS assembly, the new version includes an updated variant annotation database to enrich the analysis of variants detected in human resequencing data. These updates include dbNSFP version 4.1, new allele and gene frequencies, and a new integration with Mastermind, a database of genomic literature from Genomenon.


Twist Bioscience RUO SARS-CoV-2 NGS Assay, Biotia COVID-Dx Software

Twist Bioscience has launched its research use-only SARS-CoV-2 next-generation sequencing assay.

The capture-based assay is for detection, characterization, and environmental monitoring of the virus from nasopharyngeal, oropharyngeal, anterior nasal, and mid-turbinate nasal swabs, as well as nasopharyngeal wash/aspirates, nasal aspirates, and bronchoalveolar lavage specimens. It was validated on Illumina's NextSeq platform and includes Twist's synthetic SARS-CoV-2 RNA controls. The limit of detection is 800 viral copies/ml.

The test comes with COVID-Dx comprehensive data analysis software from Biotia, which provides an RUO report on the presence or absence of SARS-CoV-2 virus, the full sequence of the virus, genetic variants, and phylogenetic analysis.


GeneMatters Automation for Pioneer Telegenetics Platform and RISE Patient Engagement Tools

GeneMatters has added automation features to its Pioneer Telegenetics Platform and launched RISE Patient Engagement Tools to support patients undergoing genetic testing and counseling. The Pioneer Telegenetics Platform, available since 2017, is designed to integrate telehealth genetic counseling service delivery and patient management. The platform now includes several automation features designed to reduce administrative burden, provide real-time communication, and allow GeneMatters to quickly deploy custom workflows to meet partner needs.

The RISE (Reach, Inform, Support, and Educate) Patient Engagement Tools specifically support patients and can be used independently or as a complement to Pioneer, and will include modules for genetic care such as scheduling, patient triage, patient education, and results delivery.


For more new products and services, please visit the New Products page on our website.

The Scan

UK Team Presents Genetic, Epigenetic Sequencing Method

Using enzymatic DNA preparation steps, researchers in Nature Biotechnology develop a strategy for sequencing DNA, along with 5-methylcytosine and 5-hydroxymethylcytosine, on existing sequencers.

DNA Biobank Developed for French Kidney Donors, Recipients

The KiT-GENIE biobank described in the European Journal of Human Genetics contains DNA samples, genotyping profiles, immune patterns, and clinical features for thousands of kidney donors or transplant recipients in Nantes, France.

Cardiometabolic Disease May Have Distinct Associations With Microbial Metabolites in Blood, Gut

By analyzing gut microbes in combination with related metabolites in feces and blood, researchers in Nature Communications found distinct cardiometabolic disease relationships at each site.

Study Reveals New Details About Genetics of Major Cause of Female Infertility

Researchers in Nature Medicine conducted a whole-exome sequencing study of mote than a thousand patients with premature ovarian insufficiency.