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New Products Posted to GenomeWeb: Centogene, Meridian Bioscience, Oxford Nanopore, More

Centogene CentoMD 6.0

Centogene has released CentoMD 6.0, a new version of its rare disease mutation database. The latest update includes more than 465,000 patients from 120 countries, with more than 225,000 linked to Human Phenotype Ontology (HPO) terms. It contains more than 31 million unique variants, an increase of 150 percent since the last release. The number of classified and curated variants has grown to 145,000, of which about 65 percent were previously unpublished. CentoMD 6.0 also features an updated variant classification tool that follows ACMG guidelines, visualized branching structure for HPO parent and child terms, and an integrated module to show individuals who have undergone biochemical testing.


Meridian Biosciences Lyo-Ready DNA LAMP Mix

Meridian Bioscience has launched the Lyo-Ready DNA LAMP Mix to accelerate the development of ambient temperature-stable loop-mediated isothermal amplification assays. The new mix is formulated for rapid, robust, and sensitive DNA amplification through nucleic acid strand displacement, Meridian said. Its glycerol-free, 4x concentration format contains pre-optimized lyo-excipients. Once target-specific primers/probes are added, he mix is ready to be lyophilized, making it ideal for faster development LAMP assays, the company said.


Oxford Nanopore Technologies Midnight Protocol, Rapid Barcoding Kit

Oxford Nanopore Technologies has released updated protocols and kits for SARS-CoV-2 genome sequencing. The new Midnight protocol is optimized for multiplexed, high-throughput sequencing of the virus and makes use of the firm's rapid sequencing kits. It comes with a new rapid barcoding kit with 96 barcodes.


For more new products and services, please visit the New Products page on our website.

The Scan

Should've Been Spotted Sooner

Scientists tell the Guardian that SARS-CoV-2 testing issues at a UK lab should have been noticed earlier.

For Martian Fuel

Researchers have outlined a plan to produce rocket fuel on Mars that uses a combination of sunlight, carbon dioxide, frozen water, cyanobacteria, and engineered E. coli, according to Gizmodo.

To Boost Rapid Testing

The Washington Post writes that new US programs aim to boost the availability of rapid at-home SARS-CoV-2 tests.

PNAS Papers on Strawberry Evolution, Cell Cycle Regulators, False-Positive Triplex Gene Editing

In PNAS this week: strawberry pan-genome, cell cycle-related roles for MDM2 and MDMX, and more.