Bio-Rad QX One Droplet Digital PCR System
Bio-Rad this week launched the QX One Droplet Digital PCR system at the Association for Molecular Pathology meeting. The QX One is a single instrument that automates each step of the droplet digital PCR workflow including droplet generation, amplification, and droplet reading. The instrument has the capacity to run five 96-well plates simultaneously, providing the ability to analyze up to 480 samples per day. The system can detect four colors simultaneously for eight-plex CNV detection, five-plex mutation detection, and four-plex gene expression detection. It is compatible with current ddPCR supermixes, assays, and kits.
Qiagen QiaSeq Multimodal Panels
Qiagen has launched a new workflow, called QiaSeq Multimodal Panels, for the simultaneous preparation of DNA and RNA libraries for next-generation sequencing. The panels require an input as low as 10 nanograms of total nucleic acid and the workflow takes about nine hours. Both libraries are generated from the same sample and allow for the analysis of DNA variants, RNA fusions, and gene expression levels.
Paragon Genomics CleanPlex CFTR Panel
Paragon Genomics this week introduced the CleanPlex CFTR Panel for cystic fibrosis testing. The panel uses the company's CleanPlex target enrichment technology for a multiplex PCR-based targeted sequencing assay to evaluate somatic and germline variants in the CFTR gene. It covers all exons of the gene and includes mutations recommended by the American College of Medical Genetics and Genomics.
Loop Genomics Long Read Microbiome Sequencing Service
Loop Genomics has launched a new service for linked read microbiome sequencing for studies with large cohorts. For labs running at least 200 to 1,000 samples, Loop is offering 16S sequencing at a price between $38 and $20 per sample, depending on volume. Loop generates long reads using Illumina's short-read sequencing platform. The firm said it can deliver 40-fold lower error rates and can eliminate false positives, delivering species- and sometimes strain- level taxonomy.
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