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New Products Posted to GenomeWeb: Becton Dickinson, New England Biolabs, Twist Bioscience

Becton Dickinson AbSeq Immune Discovery Panel

Becton Dickinson has launched a single-tube antibody-oligo-based discovery tool called the BD AbSeq Immune Discovery Panel (IDP). The panel contains 30 different pre-titrated antibodies targeting most major immune markers, is supplied in a dried format, and allows researchers to include additional immune markers of interest. It is designed for the BD Rhapsody Single-Cell Analysis System, and intended to be used alongside protein, RNA, and multiplexing assays to enable sequencing-based immune cell phenotyping.


New England Biolabs Luna SARS-CoV-2 RT-qPCR Multiplex RUO Assay Kit

New England Biolabs has released the research-use-only Luna SARS-CoV-2 RT-qPCR Multiplex Assay Kit, which enables multiplex testing of up to 94 samples in a single 96-well plate with the additional capacity to support sample pooling and high-throughput applications using 384-well plates. The kit detects two separate regions of the SARS-CoV-2 N gene (N1 and N2) in addition to the human RNase P gene internal control, based on sequences provided by the US Centers for Disease Control and Prevention. The probes have been modified to detect N1 and N2 via two different fluorophores — HEX and FAM, respectively — for simultaneous fluorescence detection on two different channels of a real-time instrument. To reduce the risk of carryover contamination between reactions, the master mix includes dUTP and a unique, thermolabile UDG that offers significant benefits over the standard E. coli UDG, NEB said.


Twist Bioscience Synthetic RNA Controls for SARS-CoV-2 UK Variant

Twist Bioscience has begun shipping new synthetic RNA reference controls for SARS-CoV-2 that include the new variant strain of the virus (B1.1.7 lineage, variant under investigation VUI-202012/01) identified in the UK. As the new strain contains multiple mutations in the spike protein and other areas of the viral genome, some of the RT-PCR probes used widely in COVID-19 testing no longer detect the S gene that codes for the spike protein, which can lead to false negative test results. Synthetic controls for this specific mutation will enable test developers to update their testing protocols, Twist said.


For more new products and services, please visit the New Products page on our website.

The Scan

Interfering With Invasive Mussels

The Chicago Tribune reports that researchers are studying whether RNA interference- or CRISPR-based approaches can combat invasive freshwater mussels.

Participation Analysis

A new study finds that women tend to participate less at scientific meetings but that some changes can lead to increased involvement, the Guardian reports.

Right Whales' Decline

A research study plans to use genetic analysis to gain insight into population decline among North American right whales, according to CBC.

Science Papers Tie Rare Mutations to Short Stature, Immunodeficiency; Present Single-Cell Transcriptomics Map

In Science this week: pair of mutations in one gene uncovered in brothers with short stature and immunodeficiency, and more.