Beckman Coulter Life Sciences CytoFlex Mosaic Spectral Detection Module
Beckman Coulter Life Sciences, a Danaher company, has launched the CytoFlex Mosaic Spectral Detection Module for flow cytometry. When connected to the CytoFlex or S flow cytometers, the new module delivers superior fluorescence sensitivity for dim and complex multicolor experiments and can detect nanoparticles as small as 80 nm, BCLS said. The module provides two unmixing algorithms and up to 10 autofluorescence channels, with up to 88 detection channels, and the resulting richer data can help untangle the complexities of biological systems and diseases faster, with a nuanced understanding of immune cell subsets and their functions and interactions, the company said. The module is now available globally in two product configurations: CytoFlex Mosaic 88 for the CytoFlex LX Flow Cytometer and CytoFlex Mosaic 63 for the four-laser CytoFlex S Flow Cytometer.
Helix Virtual Registry of Autoimmune Disease Patients
Population genomics firm Helix has launched a new clinico-genomic virtual registry of autoimmune disease patients. The registry consists of more than 23,000 consented individuals diagnosed with conditions such as lupus, rheumatoid arthritis, psoriasis, multiple sclerosis, Hashimoto's disease, and Crohn's disease. The resource aims to provide life science researchers with new insights that may contribute to the development of new treatments for autoimmune conditions.
Objective Biotechnology Autoinjector
Objective Biotechnology, in collaboration with University of Minnesota researchers, has launched the Autoinjector, a robotic system designed to automate the microinjection process used in genetic modification protocols for tiny organisms. The system, designed through a collaboration between the University of Minnesota's Bio-Robotics and Biosensing Laboratory and the University of Minnesota Genomics Center, uses machine learning and computer vision to perform embryo injections with high speed and precision, the company said.
University of Washington Denovo-db V.1.6.1
Researchers in Evan Eichler's lab at the University of Washington have released Denovo-db version 1.6.1, a curated database of germline de novo variants in the human genome that are present in children but absent in their parents. The resource was assembled from published literature on de novo variants identified through large-scale whole-exome and whole-genome studies. The new version includes data from the Simons Simplex Collection (SSC) and was released on the UCSC Genome Browser.
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