Agena Bioscience VeriDose Core Panel v2.0
Agena Bioscience has launched the VeriDose Core Panel v2.0 for the detection of 85 variants (SNPs/INDELs) across 16 pharmacogenetic genes with Tier 1 and Tier 2 recommendations from leading societies for pharmacogenetics analysis. The panel can be run on the same plate with the VeriDose CYP2D6 CNV Panel, and the associated software provides diplotype, haplotype, and CBV data, according to Agena's website. The research-use-only panel runs exclusively on the Agena MassArray genetic analysis system.
Ansa Biotechnologies DNA Synthesis Service
Ansa Biotechnologies has launched Ansa Clonal DNA synthesis services for products up to 5 kb in length. The company's core enzymatic synthesis technology produces DNA up to 600 bp in length, which can serve as building blocks for longer molecules using a proprietary, sequence-agnostic assembly technology. The company said it can produce difficult sequences including repeats, hairpins, other strong secondary structures, GC-rich sequences, and homopolymers. Following DNA synthesis, Ansa verifies the sequence by long-read sequencing coupled with an internal informatics and analysis pipeline.
Azenta Whole-Genome Sequencing Test
Azenta has launched a long-read whole-genome sequencing test for clinical applications. The test is performed by Azenta company Genewiz through its CLIA-certified, CAP-accredited laboratory in South Plainfield, NJ, and uses Pacific Biosciences' Revio sequencer to detect a range of complex genomic alterations that are features of many rare disease and undetectable by traditional approaches, Azenta said. The assay recently received approval from the New Jersey Department of Health, allowing it to be offered clinically, a company spokesperson said.
Biofidelity Aspyre Lung Reagents
Biofidelity has launched Aspyre Lung Reagents for research use only in liquid biopsy samples. Aspyre Lung identifies established non-small cell lung cancer (NSCLC) biomarkers in both DNA and RNA from tissue and blood in a four-step workflow and runs on existing qPCR platforms. Data supporting the launch will be presented at the Association for Molecular Pathology Annual Meeting next week in Vancouver, British Columbia.
CeGaT ExomeXtra Version 6
German genetic diagnostics company CeGaT has launched an updated version of its ExomeXtra test. Version 6 incorporates noncoding splice sites and noncoding RNAs involved in splicing. Specifically, it includes small nuclear RNAs (snRNAs) of spliceosomes, with a focus on RNU4-2. It has also expanded coverage of noncoding variants to more than 46,000 targeted regions and has improved the detection of copy number variants in the genome by adding probes. In addition, the test now screens for infections relevant for prenatal diagnostics including toxoplasmosis, varicella, fifth disease, syphilis, and herpes simplex virus 1 and 2.
Genomic Testing Cooperative GTC Interpret
Genomic Testing Cooperative has launched GTC Interpret, a web-based platform designed to provide member laboratories and partner labs with access to a comprehensive range of next-generation sequencing DNA and RNA data, including sequencing quality control, detected DNA and RNA variants, tumor mutation burden, microsatellite instability, homologous recombination deficiency, Epstein-Barr virus, human papillomavirus, and torque teno virus (TTV). Users can also access details on MET14, EGFRviii, and other genes, alternative splicing data, RNA fusions, chromosomal changes, gene copy numbers, HLA genotyping, RNA expression levels, B-cell (heavy and light chains) and T-cell clonality (T-cell receptors of alpha, beta, gamma, and delta genes) with their specific clonotype, the company said. The platform also gives access to BAM file images highlighting and comparing detected DNA and RNA variants allowing for a clear, visual confirmation of results, GTC added.
Omega Bio-Tek Mag-Bind Endo-Free Plasmid Mini & Midi Kits
Omega Bio-Tek has launched Mag-Bind Endo-Free Plasmid Mini & Midi magnetic bead-based kits for purifying endotoxin-free plasmid DNA. The kits use a modified alkaline lysis method to form a bacterial lysate that can then be cleared using Mag-Bind Particles LC beads, the use of which enables full automation of the purification process. The kits can be automated on most open-ended liquid handlers and magnetic processors, including Omega Bio-Tek's MagBinder Fit24 platform. The Mini kit purifies plasmids from up to 1.5 mL of overnight bacterial culture in LB, TB, or other suitable growth media; while the Midi kit is optimized for purifying plasmids from up to 50 mL of bacterial culture in LB or 10 mL in TB, the company said.
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