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NanoCellect Biomedical Receives $1.5M NIH Grant to Develop 3D Flow Cytometry Tool

NEW YORK – NanoCellect Biomedical said today that the National Institutes of Health has awarded the firm a $1.5 million Phase II Small Business Innovation Research grant to further develop its imaging flow cytometry technology.

As part of the two-year project, the San Diego-based firm aims to demonstrate a high-throughput flow cytometry system that sorts cells based on high-content 3D features. NanoCellect said that the system will produce a cell tomography from spatially resolved fluorescence and scattering signals at a rate of 1,000 cells per second. 

In addition, the firm noted that the flow cytometry tool will reconstruct each multi-parameter 3D cell image, extract hundreds of image features, and sort user-defined cell criteria for ongoing single-cell analysis. 

NanoCellect said that system will combine the strengths of high throughput cell analysis and sorting capabilities of a fluorescence-activated cell sorter with a high-content 3D imaging microscope to enable researchers to analyze, classify, and isolate cells at single-cell resolution. 

"Extending from our WOLF platform, NanoCellect has developed a method of spatial-temporal transformation to provide flow cytometers with cell imaging capabilities," NanoCellect Cofounder Will Alaynick said in a statement. "This program represents an important scientific validation, and we're delighted to receive this Phase II NIH grant to expand the scientific boundaries of cellular analysis to enable new discoveries and improve biomedical research." 

NanoCellect partnered with Seoul-based Daon Biosciences in May to distribute NanoCellect's technology in the South Korean market.