Skip to main content
Premium Trial:

Request an Annual Quote

Myriad RBM, Institut Pasteur to Field Test Platform for TB

NEW YORK (GenomeWeb) – Myriad RBM, a wholly owned subsidiary of Myriad Genetics, today said it is collaborating with Institut Pasteur to field test Myriad RBM's TruCulture as a point-of-care blood collection and immune response monitoring method and to stratify patients with active and latent tuberculosis. 

Funded by a grant from the Bill & Melinda Gates Foundation to Institut Pasteur, the proof-of-concept study will evaluate patients affiliated with the South African Tuberculosis Vaccine Initiative clinical study sites and who have latent or active TB. Using Myriad RBM's MAP platform, the partners aim to discover protein biomarkers that are crucial in regulating immune system response.

In a statement, Matthew Albert, co-coordinator of Milieu Interieur and director of the immunology department at Institut Pasteur, said that earlier studies support the use of the TruCulture system in settings with limited resources, "and may help us improve the diagnosis of TB and accelerate the development of new drugs and vaccines to treat the disease." 

The TruCulture system captures immune cell activity and uses a single, self-contained tube for whole blood collection and culture. 

Myriad RBM President Ralph McDade added that the collaboration will result in better treatments and better support for vaccine clinical trials. "If we are successful, TruCulture may prove to be useful in a multitude of field-based, point-of-care applications, leading to improved patient care," he said. 

The Scan

UCLA Team Reports Cost-Effective Liquid Biopsy Approach for Cancer Detection

The researchers report in Nature Communications that their liquid biopsy approach has high specificity in detecting all- and early-stage cancers.

Machine Learning Improves Diagnostic Accuracy of Breast Cancer MRI, Study Shows

Combining machine learning with radiologists' interpretations further increased the diagnostic accuracy of MRIs for breast cancer, a Science Translational Medicine paper finds.

Genome Damage in Neurons Triggers Alzheimer's-Linked Inflammation

Neurons harboring increased DNA double-strand breaks activate microglia to lead to neuroinflammation like that seen in Alzheimer's disease, a new Science Advances study finds.

Long COVID-19 Susceptibility Clues Contained in Blood Plasma Proteome

A longitudinal study in eBioMedicine found weeks-long blood plasma proteome shifts after SARS-CoV-2 infection, along with proteomic signatures that appeared to coincide with long Covid risk.