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Celsee, IncellDx to Commercialize Assays After Cancer Study Collaboration

NEW YORK (GenomeWeb) – Celsee said today that it has entered a co-commercialization agreement with IncellDx for several products, including a 20-marker lung cancer genomics and proteomics panel, a CTC-based screening test for breast, colorectal, prostate, and other cancers, and a cell-based NIPT assay.

The companies said that their announcement follows the successful completion of a feasibility study that analyzed PD-L1 expression in lung cancer biopsy and blood specimens using the IncellDx OncoTect iO Single Cell Quantitative PD-L1 assay and the Celsee C-Prep Genesis platform.

In the study, which was presented last year at the annual meeting of the Association for Molecular Pathology, several patient samples showed a positive expression for PD-L1 in CTCs using the companies' combined technologies, but showed only minimal expression using standard-of- care methods.

"The coupled ability of IncellDx's technology to generate single cell suspensions with Celsee's technology to isolate and analyze single cells derived from peripheral blood and tissue will create a new standard for clinical research and for future diagnostic applications," Celsee CEO John Stark said in a statement.

Financial terms of the agreement were not disclosed.


The Scan

Guidelines for Ancient DNA Work

More than two dozen researchers have developed new ethical guidelines for conducting ancient DNA research, which they present in Nature.

And Cleared

A UK regulator has cleared former UK Prime Minister David Cameron in concerns he should have registered as a consultant-lobbyist for his work with Illumina, according to the Financial Times.

Suit Over Allegations

The Boston Globe reports that David Sabatini, who was placed on leave from MIT after allegations of sexual harassment, is suing his accuser, the Whitehead Institute, and the institute's director.

Nature Papers on Esophageal Cancer, Origin of Modern Horses, Exome Sequencing of UK Biobank Participants

In Nature this week: genetic and environmental influences of esophageal cancer, domestic horse origin traced to Western Eurasian steppes, and more.