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Bioo Licenses NGS Technology from Icahn School of Medicine

NEW YORK (GenomeWeb) – Bioo Scientific today announced it has licensed randomized adapter technology from the Icahn School of Medicine at Mount Sinaifor reducing ligation bias in next-generation sequencing. 

Bioo has incorporated the technology into its Nextflex Small RNA-Seq Library Prep Kit v.2. 

Because no single adapter sequence can efficiently ligate to all small RNAs, the target sequence and the adapter sequence can be a source of bias, according to the Austin, Texas-based firm. The technology developed by Icahn School researchers uses a pool of adapters containing randomized sequences at the ligation site to allow small RNAs of any sequence to locate their respective optimal adapters. The result is that RNA libraries have a "dramatic reduction in bias," Bioo said. 

"Through our partnership with Bioo Scientific, we hope to make this technology available to all researchers interested in improving the accuracy of their small RNA-seq analysis," Ravi Sachidanandam, assistant professor of oncological sciences at the Icahn School, said in a statement. Sachidanandam initially investigated small RNA-seq bias reduction using randomized adapters. 

Financial and other terms of the deal were not disclosed.