Skip to main content
Premium Trial:

Request an Annual Quote

Biocept, Insight Genetics to Collaborate on Lung Cancer Molecular Diagnostic

NEW YORK (GenomeWeb) – Molecular diagnostics firms Biocept and Insight Genetics today announced that they will collaborate on the development of a test designed to detect the expression and mutation of ALK, a gene involved in signal transduction and a therapeutic target for non-small cell lung cancer.

Under the deal, Biocept will use its proprietary technologies for capturing and analyzing circulating tumor cells and circulating tumor DNA in blood samples. Insight Genetics will then apply its technologies to determine ALK expression and track whether the gene mutates over the course of patient treatment.

The initial aim of the collaboration is to better identify and monitor patients who may benefit from existing ALK-targeting treatments, as well as those who may benefit from second-generation therapies based on inhibitor resistance mechanisms, the companies added.

Additional terms of the arrangement were not disclosed.

The Scan

UK Pilot Study Suggests Digital Pathway May Expand BRCA Testing in Breast Cancer

A randomized pilot study in the Journal of Medical Genetics points to similar outcomes for breast cancer patients receiving germline BRCA testing through fully digital or partially digital testing pathways.

Survey Sees Genetic Literacy on the Rise, Though Further Education Needed

Survey participants appear to have higher genetic familiarity, knowledge, and skills compared to 2013, though 'room for improvement' remains, an AJHG paper finds.

Study Reveals Molecular, Clinical Features in Colorectal Cancer Cases Involving Multiple Primary Tumors

Researchers compare mismatch repair, microsatellite instability, and tumor mutation burden patterns in synchronous multiple- or single primary colorectal cancers.

FarGen Phase One Sequences Exomes of Nearly 500 From Faroe Islands

The analysis in the European Journal of Human Genetics finds few rare variants and limited geographic structure among Faroese individuals.