NEW YORK (GenomeWeb News) – The stock of Quest Diagnostics this week was downgraded by Zacks Equity Research to Underperform. In a statement, the investment research and information firm noted a drop in Quest's revenues and earnings-per-share for continuing operations in the fourth quarter, as well as a "disappointing outlook" for the first quarter of 2013.

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In Science this week: the Human Silencing Hub protein complex, and more.

Heads of various research funding agencies discuss how to encourage scientific breakthroughs, ScienceInsider reports.

The Kansas City Star examines issues surrounding newborn genome sequencing.

Researchers say their Research Resource Identifier citation format is catching on, Nature News reports.