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In Brief This Week: OncoDNA, Interpace Diagnostics, CeCaVa, and More

NEW YORK (GenomeWeb) – OncoDNA said this week that new guidelines from the Spanish Society of Pathology and the Spanish Society of Medical Oncology now endorse genomic testing to identify cancers of unknown primary origin using tools like OncoDNA's OncoDEEP product: a combined DNA and protein assay performed on solid tumor samples.

The company presented data at the annual congress of the Spanish Society of Medical Oncology last month showing that OncoDEEP could be used to identify the origins of a tumor in more than 80 percent of cases and could detect potentially actionable mutations in more than 60 percent of cases.


Interpace Diagnostics reported this week that it has entered into an agreement with Piedmont Healthcare, Georgia's largest healthcare system, enabling all physicians in the Piedmont Healthcare Network to use the company's PancraGen molecular pancreatic cancer risk classifier for patients with indeterminate pancreatic cysts or other pancreaticobiliary lesions. Interpace recently announced an expansion of the applications for PancraGen to include biliary strictures and solid lesions.


Medical technology and pharmaceutical manufacturer B. Braun Melsungen and CeGaT this week announced the creation of a joint venture called CeCaVa GmbH & Co. to develop individualized vaccines to treat diseases, particularly tumorous diseases. CeCaVa, based in Tübingen, Germany stands for Center for Cancer Vaccines. CeGaT will contribute its expertise in genetic tumor diagnostics. Aesculap AG, a subsidiary of B. Braun Melsungen, will provide operational support.


Premaitha this week said it has signed a new partnership agreement between its Yourgene Bioscience division and an unspecified clinical research organization in Taiwan. Under the terms of the partnership, Yourgene will provide genetic testing services using NGS technology on patient samples gathered by the partner for the purpose of research into early-stage cancer screening. The collaborators anticipate the project will also have additional phases. The initial phase is anticipated to generate approximately $1 million of revenues over the next six to 12 months, Premaitha said.


In Brief This Week is a selection of news items that may be of interest to our readers but had not previously appeared on GenomeWeb.

The Scan

UK Pilot Study Suggests Digital Pathway May Expand BRCA Testing in Breast Cancer

A randomized pilot study in the Journal of Medical Genetics points to similar outcomes for breast cancer patients receiving germline BRCA testing through fully digital or partially digital testing pathways.

Survey Sees Genetic Literacy on the Rise, Though Further Education Needed

Survey participants appear to have higher genetic familiarity, knowledge, and skills compared to 2013, though 'room for improvement' remains, an AJHG paper finds.

Study Reveals Molecular, Clinical Features in Colorectal Cancer Cases Involving Multiple Primary Tumors

Researchers compare mismatch repair, microsatellite instability, and tumor mutation burden patterns in synchronous multiple- or single primary colorectal cancers.

FarGen Phase One Sequences Exomes of Nearly 500 From Faroe Islands

The analysis in the European Journal of Human Genetics finds few rare variants and limited geographic structure among Faroese individuals.