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In Brief This Week: Luminex; Qiagen; Life Technologies; AvanDx; Monogram Biosciences; and CombiMatrix

NEW YORK (GenomeWeb News) – Luminex this week announced that it has opened a new office in Shanghai, People's Republic of China, to serve as its center of operations in the Asia-Pacific region. The firm said that the office will include training lab space and a full-time staff, though it did not provide an expected number of employees. Luminex also has operations at its headquarters in Austin, Texas, and offices in Toronto and Oosterhout, The Netherlands.

Qiagen this week said that it had CE marked its next-generation KRAS test for colorectal cancer and has launched the assay. The firm said it is an updated version of its first pyrosequencing-based assay for personalized cancer treatment.

Life Technologies said this week that researchers at bioMérieux and the Institute of Analytical Sciences of the University of Lyon in France are using the AB SCIEX QTRAP 5500 System in a biomarker collaboration.

AdvanDx said this week that Memorial University Medical Center in Savannah, Ga., is using its PNA FISH tests to identify bloodstream pathogens one to three days earlier than conventional methods.

Monogram Biosciences said that it presented three studies at the American Society for Clinical Oncology meeting earlier this week that demonstrated the ability of its HERmark and VeraTag technologies in identifying distinct sub-populations of patients with HER-positive disease.

CombiMatrix said this week that researchers from its CombiMatrix Molecular Diagnostics subsidiary and from the University of Texas Health Science Center in San Antonio published a validation study on its HerScan array-based test in the journal Modern Pathology. The test facilitates subtyping of breast cancers into five different subtypes that are cytogenetically characteristic, CombiMatrix said.

The Scan

Study Points to Tuberculosis Protection by Gaucher Disease Mutation

A mutation linked to Gaucher disease in the Ashkenazi Jewish population appears to boost Mycobacterium tuberculosis resistance in a zebrafish model of the lysosomal storage condition, a new PNAS study finds.

SpliceVault Portal Provides Look at RNA Splicing Changes Linked to Genetic Variants

The portal, described in Nature Genetics, houses variant-related messenger RNA splicing insights drawn from RNA sequencing data in nearly 335,700 samples — a set known as the 300K-RNA resource.

Automated Sequencing Pipeline Appears to Allow Rapid SARS-CoV-2 Lineage Detection in Nevada Study

Researchers in the Journal of Molecular Diagnostics describe and assess a Clear Labs Dx automated workflow, sequencing, and bioinformatic analysis method for quickly identifying SARS-CoV-2 lineages.

UK Team Presents Genetic, Epigenetic Sequencing Method

Using enzymatic DNA preparation steps, researchers in Nature Biotechnology develop a strategy for sequencing DNA, along with 5-methylcytosine and 5-hydroxymethylcytosine, on existing sequencers.