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In Brief This Week: Hologic, PercayAI, Guardant Health, and More

NEW YORK – Hologic this week announced a multi-year strategic collaboration tintegrate Google Cloud's machine learning technologies with Hologic's Genius Digital Diagnostics System. Genius Digital Diagnostics is a digital cytology platform that combines artificial intelligence with advanced digital imaging to help identify pre-cancerous lesions and cancer cells in women.

Hologic said Google Cloud enhances the system's deep learning component. With Google Cloud, the Genius Digital Diagnostics System is expected to derive more actionable insights from cytology slides for cytotechnologists and pathologists, Hologic said.

Financial terms of the collaboration were not disclosed.

PercayAI said this week that researchers at Saint Louis University are using its augmented intelligence-based drug discovery platform to look for "non-obvious contextual signals" to help researchers identify novel potential drug targets. The work has started with RNA sequencing data, but will expand to other genomic and phenotypic data, according to the company.

As part of the collaboration, computational biologists and machine learning engineers from St. Louis-based PercayAI will train SLU faculty and students on the platform, which includes CompBiosoftware that applies AI artificial intelligence and contextual language processing to help researchers identify relationships within multi-omic datasets to inform drug discovery.

Guardant Health’s Asia, Middle East & Africa division this week submitted its application to Japan's Ministry of Health, Labour and Welfare for regulatory approval of the Guardant360 CDx assay for comprehensive genomic profiling in patients with advanced solid tumors and as an unspecified companion diagnostic.

Guardant360 CDx, a blood-based liquid biopsy test, analyzes circulating tumor DNA and identifies genetic alterations that may inform treatment decisions. Last August, the US Food and Drug Administration approved the test for comprehensive genomic profiling across solid tumors and as a companion diagnostic to identify non-small cell lung cancer patients with EGFR alterations who may benefit from treatment with osimertinib (AstraZeneca's Tagrisso).

Quidel announced this week that it will open a new manufacturing facility for its QuickVue line in Carlsbad, California. The 128,000-square-foot facility will begin operations in the second half of 2021 and will be the company’s highest-volume production plant, expected to produce 600 million QuickVue SARS rapid antigen tests per year for the detection and diagnosis of COVID-19 infections. Quidel said it will install multiple manufacturing lines at the Carlsbad facility and will hire approximately 400 new employees to scale its operations from 50 million QuickVue tests per year to 50 million tests per month at full capacity, including non-COVID-19 diagnostic assays currently commercially available or under development. The firm also said it is currently hiring engineers, chemists, and technicians, as well as for positions in manufacturing, purchasing, sourcing, and support services.

The American Association of Clinical Chemistry announced this week that it has sold its Lab Tests Online resource on laboratory testing to digital health company OneCare Media. Lab Tests Online helps people better understand clinical laboratory tests, the AACC said, and added that the agreement with OneCare Media will allow the site to expand its scope and reach more consumers. Under the terms of the agreement, OneCare will have an expert advisory board for the site and one third of that board will be members of AACC. Financial terms of the deal were not disclosed. OneCare Media’s other sites include,, and

Revelation Biosciences said this week it has closed a private placement that raised $4.4 million in gross proceeds. National Securities, a wholly owned subsidiary of National Holdings, was the exclusive placement agent on the Series A-1 preferred stock financing. Menlo Park, California-based Revelation sold 684,444 shares of the preferred stock at a purchase price of $6.36 per share. It said that it has raised $14.5 million in total gross proceeds to dateThe company plans to use the proceeds from the most recent financing for working capital and the development of its REVDx-501, a diagnostic test for upper respiratory viral infections including COVID-19, and REVTx-99, a therapy for respiratory viral infections. The financing will also go toward general administrative operations.

Seer this week closed its public offering of 3,750,000 shares of Class A common stock at an offering price of $67 per share, of which 1,650,000 were sold by Seer and 2,100,000 were sold by selling stockholders of the firm. Gross proceeds from the offering to Seer were around $110.5 million.

The Access to Comprehensive Genomic Profiling Coalition this week appointed NeoGenomics and Tempus to its coalition of diagnostic firms and laboratory service providers to advocate for appropriate broad US health insurance coverage of comprehensive genomic profiling for patients living with advanced cancer.

Bio-Techne said this week that its board will pay a dividend of $.32 per share for the quarter ended Dec. 31, 2020, payable on Feb. 26 to common shareholders of record on Feb. 12.

In Brief This Week is a selection of news items that may be of interest to our readers but had not previously appeared on GenomeWeb. 

The Scan

Genetic Testing Approach Explores Origins of Blastocyst Aneuploidy

Investigators in AJHG distinguish between aneuploidy events related to meiotic missegregation in haploid cells and those involving post-zygotic mitotic errors and mosaicism.

Study Looks at Parent Uncertainties After Children's Severe Combined Immunodeficiency Diagnoses

A qualitative study in EJHG looks at personal, practical, scientific, and existential uncertainties in parents as their children go through SCID diagnoses, treatment, and post-treatment stages.

Antimicrobial Resistance Study Highlights Key Protein Domains

By screening diverse versions of an outer membrane porin protein in Vibrio cholerae, researchers in PLOS Genetics flagged protein domain regions influencing antimicrobial resistance.

Latent HIV Found in White Blood Cells of Individuals on Long-Term Treatments

Researchers in Nature Microbiology find HIV genetic material in monocyte white blood cells and in macrophages that differentiated from them in individuals on HIV-suppressive treatment.