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In Brief This Week: Grail, Stilla Technologies, SpeeDx, and More

NEW YORK (GenomeWeb) – Grail announced this week that the US Food and Drug Administration has granted breakthrough device status to the firm's multi-cancer test. Grail is developing its investigational liquid biopsy for early detection of cancer in people aged 50 or older.

Stilla Technologies said this week that it has signed a three-year collaborative agreement with Ghent University for training, research, and exploration of novel applications of digital PCR. The partners plan to offer dPCR users hands-on training courses, webinars, and seminars in on dPCR. They're also aiming to optimize and validate assays based on Stilla's Naica dPCR system for a broad range of experiments, and provide a platform for users to validate their samples on the Naica system with the help of dPCR experts from the university. The Naica system offers multiplexing to detect multiple target genes in a single assay with high precision and accuracy.

SpeeDx said this week that its PlexPCR RespiVirus test has received regulatory clearance from the Australian Therapeutic Goods Administration. The assay uses PlexPCR technology to detect 11 viral respiratory illness-causing pathogens including influenza A, influenza B, rhinovirus, respiratory syncytial viruses (A and B), human metapneumovirus, adenovirus, and human parainfluenza viruses 1, 2, 3, and 4.

Quest Diagnostics this week announced a quarterly cash dividend of $.53 per share, payable on July 22 to shareholders of record on July 8.

In Brief This Week is a selection of news items that may be of interest to our readers but had not previously appeared on GenomeWeb.

The Scan

Study Examines Insights Gained by Adjunct Trio RNA Sequencing in Complex Pediatric Disease Cases

Researchers in AJHG explore the diagnostic utility of adding parent-child RNA-seq to genome sequencing in dozens of families with complex, undiagnosed genetic disease.

Clinical Genomic Lab Survey Looks at Workforce Needs

Investigators use a survey approach in Genetics in Medicine Open to assess technologist applications, retention, and workforce gaps at molecular genetics and clinical cytogenetics labs in the US.

Study Considers Gene Regulatory Features Available by Sequence-Based Modeling

Investigators in Genome Biology set sequence-based models against observational and perturbation assay data, finding distal enhancer models lag behind promoter predictions.

Genetic Testing Approach Explores Origins of Blastocyst Aneuploidy

Investigators in AJHG distinguish between aneuploidy events related to meiotic missegregation in haploid cells and those involving post-zygotic mitotic errors and mosaicism.