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The researchers found that the diversity of epithelial cell types was reduced in nasal polyps, which contained few glandular and ciliated cells and were enriched in basal cells.

Their analyses of this individual's genome suggested to the researchers that admixture among archaic and modern hominin groups was likely common.

The transcriptomes of recessive dystrophic epidermolysis bullosa squamous cell carcinoma also suggested a role for inflammation in disease development.

The study identified four variants in BAG3 that almost only occurred in African Americans and were associated with a nearly twofold increase in cardiac events.

Pfizer will join Exact's sales reps to increase adoption of the colorectal cancer test; Wall Street reacted by sending Exact's shares up sharply.

Researchers screened 2,000 Nigerian women with and without the disease for loss-of-function mutations in 25 known and suspected breast cancer genes.

The working group reviewed data to identify a minimum of 34 commonly mutated genes that should be included in pan-myeloid targeted panels.

Oxford BioDynamics has developed a platform for discovering, evaluating, validating, and monitoring a unique class of epigenetic biomarkers.

The company said it saw record-setting growth in new products in fiscal 2018 with increasing reimbursement adding to its hereditary cancer business.

The group described a five-tiered classification system for cancer-associated genomic alterations that they hope could be implemented globally.

The company's offering of 3.36 million units at $6.125 per unit — each consisting of one share of common stock and one warrant — is expected to close Aug. 23.

Physicians can now use the Dako PD-L1 IHC 22C3 pharmDx assay to identify urothelial carcinoma patients who may benefit from the anti-PD1 immunotherapy.

The company uses genome editing technologies for agricultural and biomedical applications, including therapeutic cell, tissue, and organ generation.

In response to public comment on draft recommendations published last year, the USPSTF changed course and retained cotesting as an option.

The companies will incorporate PerkinElmer's LabChip GX Touch nucleic acid analyzer in the upfront workflow of Agena's MassArray system.

The firm plans to make the molecular testing system accessible to low-income countries, in part by reducing costs using reel-to-reel manufacturing.

According to Caprion, the company plans to use Primity's assets to expand its existing immunology and molecular profiling business.

The predictor, based on 15 pairwise relations between immune checkpoint genes, identified almost all true responders and misclassified fewer than half of non-responders.

MBio will use the funding to refine its diagnostic tool and to improve manufacturing as the firm scales up to support its commercialization partners.

The filing follows the firm's recent close of a $2 million non-convertible debt instrument and CE marking for its tuberculosis test.

TSG is a wholly owned subsidiary of Ascendis Medical and supplies diagnostic laboratory equipment and consumables to pathology laboratories.

A study found that cis-regulatory variation modifies the penetrance of coding variants, and that variants' regulatory haplotype configuration affects disease risk.

Plasmodium vivax parasites that infect humans have highly similar genomes to parasites that infect apes, a finding with possible disease-eradication consequences.

Last week, GenomeWeb's readers were most interested in Illumina's launch of a $650 million senior notes offering.

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The New York Times and ProPublica look into the close relationship between a startup and Memorial Sloan Kettering Cancer Center.

Yahoo News reports millions of dollars are being transferred from NIH, CDC, and other programs to pay for the housing of detained undocumented immigrant children.

In Science this week: in vitro generation of human reproductive cells, and more.

Researchers gave a handful of octopuses MDMA to find that they too act more social on the drug, Gizmodo reports.