The researchers found that the diversity of epithelial cell types was reduced in nasal polyps, which contained few glandular and ciliated cells and were enriched in basal cells.
The transcriptomes of recessive dystrophic epidermolysis bullosa squamous cell carcinoma also suggested a role for inflammation in disease development.
The study identified four variants in BAG3 that almost only occurred in African Americans and were associated with a nearly twofold increase in cardiac events.
The company's offering of 3.36 million units at $6.125 per unit — each consisting of one share of common stock and one warrant — is expected to close Aug. 23.
Physicians can now use the Dako PD-L1 IHC 22C3 pharmDx assay to identify urothelial carcinoma patients who may benefit from the anti-PD1 immunotherapy.
The predictor, based on 15 pairwise relations between immune checkpoint genes, identified almost all true responders and misclassified fewer than half of non-responders.
A study found that cis-regulatory variation modifies the penetrance of coding variants, and that variants' regulatory haplotype configuration affects disease risk.
Plasmodium vivax parasites that infect humans have highly similar genomes to parasites that infect apes, a finding with possible disease-eradication consequences.
Yahoo News reports millions of dollars are being transferred from NIH, CDC, and other programs to pay for the housing of detained undocumented immigrant children.
