Researchers saw variants contributing to both ends of the weight spectrum by analyzing thousands of thin, early-onset obese, and population control individuals.
The institutes will send patients samples to Resolution Bioscience, which will sequence circulating tumor DNA to identify the genetic causes of drug resistance.
The effort, led by BGI-Shenzen researchers, could help further plant sequencing studies and inform upcoming large-scale plant sequencing plans.
The firm will use the proceeds for working capital, capital payments, business development, research and development payments, and technology and business acquisitions.
Decode Genetics researchers used the map to examine how often and where recombination events and de novo mutations occur in the human genome.
In a new policy paper, investigators outlined existing challenges to public data sharing and touted the benefits of increasing openness before and after publication.
The data analysis pipeline will allow users to pre-process raw InDrop single-cell RNA-seq data and use Partek tools to characterize single cells.
The firm lowered topline and non-GAAP earnings per share guidance for fiscal 2019.
The project has signed up about 170,000 participants so far, of whom 100,000 are fully enrolled, and plans to enhance recruitment through pop-up clinics.
The FDA said it is the first test authorized to test for M. genitalium, a slow-growing bacteria that is difficult to detect with traditional laboratory methods.
The firm said it raised €55.5 million to fund the expansion of its Idylla test platform, its sales and marketing activities, and other general corporate purposes.
Three long-read assemblies — two from PacBio data alone and one from Oxford Nanopore and Illumina data — had considerably more indel errors in genes than short-read assemblies.
The company, which employs 300 people, axed 30 jobs in the US and 25 jobs from its overseas operations as it refocuses on therapeutic development.
The deal covers distribution of the SpeeDx ResistancePlus and PlexPCR assays.
The Boston-based startup will use the funds to expedite prototype development of its sample preparation technology and computational approach.
Driven by strong pharma sales, revenues increased to $715 million from $687 million in Q4 2017, besting the consensus analyst estimate of $703 million.
Researchers traced genomic, epigenomic, and expression features in lung carcinoma in situ cases that regressed or progressed to invasive lung squamous cell carcinomas.
Alere rapid diagnostics revenues were $548 million in the quarter, driven by infectious disease and cardiometabolic testing product sales.
The Belgium-based firm plans to use the proceeds to fund expansion of the Idylla test platform, sales and marketing activities, and additional general corporate purposes.
The firm will use the funds to improve market entry and expedite development of its artificial intelligence-based software that analyzes single-cell data.
Cancer Research UK has awarded nearly £60 million in funding to three US investigator-led research initiatives focused on cancer progression and drug response.
The nuclease, which comes from Bacillus hisashii, has gain-of-function mutations that facilitate robust editing in human cell lines and primary human T cells.
The researchers found that low-frequency variants in TP53 had a large effect on head circumference and volume, suggesting a previously unknown role for the gene.
Oxford Nanopore had challenged the validity of the patent, EP3045542, which relates to DNA sample preparation for PacBio's circular consensus sequencing.
The Hill reports President Donald Trump issued an executive directing federal agencies to cut the number of board and advisory committees they have.
The New York Times reports that researchers are combining tools to more quickly develop crops to feed a growing population and cope with shifting climates.
Scientists in Canada are looking to the UK's plan to sequence children with rare conditions for inspiration, the National Post reports.
In PNAS this week: copy number changes arose during polar bear evolution, genomic and transcriptomic analysis of the Siberian hamster, and more.