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AstraZeneca and Merck also announced they have filed for approval of Lynparza in patients who have mutations in more than a dozen homologous recombination repair genes.

Researchers used Fluidigm's Hyperion Imaging System to quantify 35 protein biomarkers and examine the phenotypes and organization of single cells within breast tumors.

An international group of researchers aim to develop an approach that may be able to diagnose multiple conditions, including pneumonia, tuberculosis, sepsis, with one blood sample.

News items for the week of Jan. 13, 2020.

The European Patent Office appeals board upheld the decision made by the EPO after its initial review in 2018.

The deal covers distribution of certain of Primerdesign's molecular testing products to the aquaculture and aquamarine markets in France.

CHOP researchers uncovered CNV associations with four disease categories: autoimmune, cardio-metabolic, oncologic, and neurological/psychiatric diseases.

The federal court order dismissed the case with prejudice, which prevents the plaintiffs from raising the case again.

The Scottish bioinformatics firm will crunch multi-omic datasets to assist Charles River Laboratories in "data-driven" drug discovery.

Exact Sciences CEO Kevin Conroy discussed the firm's pipeline and plans for 2020 and beyond, while NanoString CEO Brad Gray talked about the company's GeoMx digital spatial profiling technology, among other presentations Wednesday.

The firm also has an early-access program for a new amplification strategy that combines 11 HLA genes for typing.

Three new studies have found that the presence of B cells in tertiary lymphoid structures in tumors is associated with a favorable response to immunotherapy.

The results suggest patients receiving stem cell transplants for blood cancers may be at increased risk of somatic mutation-related complications even with young bone marrow donors.

A genome-wide association study uncovered six loci associated with heavy drinking and additional analysis found ties to other conditions including lung cancer.

Illumina, Twist Bioscience, and DNA Script are among the private sector collaborators of the groups receiving funds to develop technology platforms.

The financing round comes as Color expands its partnerships with healthcare systems and builds out a national genetic counseling resource for NIH's All of Us program.

The group will create a kitted next-generation sequencing tool that will help researchers and biopharma firms conduct biomarker discovery work on patient blood samples.

The test adds to a menu of transplant monitoring assays that includes cytomegalovirus, Epstein-Barr virus, and BK virus.

The company has rehired a core team of employees and is working on closing a "significant round of funding" from undisclosed potential investors or partners.

On the second day of the conference, updates came not just from the publicly traded industry giants but also privately held firms of interest, such as Caris and GenapSys.

Called Theta, Single Technologies' platform relies on automated fluidics and single molecule-sensitive imaging to improve sequencing throughput.

By analyzing the genomes of the admixed descendants of the vanished Brazilian coastal Tupí population, researchers worked out how they likely settled there thousands of years ago.

While de novo mutations appeared to make relatively modest contributions to schizophrenia risk, they recurrently affected evolutionarily conserved genes.

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An initial analysis suggests the novel coronavirus from Wuhan that is sickening people might come from snakes, a team of virologists writes at the Conversation.

DNA testing confirms captured Chicago coyote same as the one that bit a boy near a nature museum, the Chicago Tribune reports.

An analysis of Tibetan ice cores uncovers more than two dozen previously unknown virus groups, LiveScience reports.

In Nature this week: genomic analysis of four children buried in Cameroon approximately 3,000 and 8,000 years ago, and more.