Using whole-genome sequencing, the researchers uncovered pathogenic variants in cancer-predisposing genes in 15 percent of patients with multiple primary tumors.
With sequence data for more than 118,000 tumors profiled at Foundation Medicine, investigators tracked PDL1 amplification prevalence and possible treatment implications.
The researchers used 10X Genomics' linked-read genome sequencing approach to home in on rearrangements that affect the androgen receptor locus and its enhancer.
New tumor profiling papers stemming from prior clinical trials led to informative mutations in early-stage, ER+/HER2- breast cancer and lung squamous cell carcinoma.
An association study involving more than 100,000 individuals led to overlapping and distinct variants involved in bipolar disorder, schizophrenia, and subtypes of each.
Benchmark led a new investment round in digital lab notebook maker Benchling, which claims 500 percent year-over-year growth in annual recurring revenue.
With panel sequencing data for more than 143,000 individuals, researchers characterized intragenic copy number variants in hundreds of monogenic disease genes.
The companies will offer free testing to more rapidly identify individuals with certain mutations, supporting Inozyme's efforts to develop and test new treatments.
Researchers analyzed a dozen genomes from individuals who lived in Morocco or Iberia during the Neolithic to find a complex population history in North Africa.
The Somatic Cell Genome Editing program was established earlier this year to help remove barriers from the adoption of genome editing for treating patients.
By analyzing more than 100 testicular germ cell tumors, investigators characterized mutation, methylation, and other patterns in four histological subtypes of the disease.
The firm said that the decline was due to a customer shifting to internalizing genetic ordering, adverse weather, and the loss of an undisclosed commercial payor.
At ASM Microbe, the University of Wisconsin's Caitlin Pepperell described her work putting Mycobacterium tuberculosis genomics into a historical context.
A draft bill released by the US House of Representatives appropriations committee would increase the 2019 National Institutes of Health budget by 3 percent.
