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Book Review

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Pyrosequencing Protocols
Edited by Sharon Marsh

This technical book provides in-depth, step-by-step protocols for using pyrosequencing technology. Entries are written by scientists from a number of institutions, including Uppsala University, Washington University School of Medicine, and the University of Pittsburgh, among others. Topics cover everything from the history of pyrosequencing technology to primer applications, methylation analysis, and gene copy number.
Publisher: Humana Press
Publication date: November 17, 2006
ISBN: 1-588-29-645-8

Biochips as Pathways to Drug Discovery
Edited by Andrew Carmen and Gary Hardiman

In this book, editors Carmen and Hardiman delve into the topic of DNA biochips and their uses in the pharmaceutical world. Covering topics such as ChIP-chip studies, SNP analysis, and expression profiling, they and the other contributors look at the use of microarrays to reduce the cost and improve the efficiency of the drug discovery process. Contributors include Francis Barany, Gary Williamson, and Elizabeth Winzeler.
Publisher: CRC Press
Publication date: 2007
ISBN: 1-57444-450-6

 

The Scan

Latent HIV Found in White Blood Cells of Individuals on Long-Term Treatments

Researchers in Nature Microbiology find HIV genetic material in monocyte white blood cells and in macrophages that differentiated from them in individuals on HIV-suppressive treatment.

Seagull Microbiome Altered by Microplastic Exposure

The overall diversity and the composition at gut microbiome sites appear to coincide with microplastic exposure and ingestion in two wild bird species, according to a new Nature Ecology and Evolution study.

Study Traces Bladder Cancer Risk Contributors in Organ Transplant Recipients

In eLife, genome and transcriptome sequencing reveal mutation signatures, recurrent somatic mutations, and risky virus sequences in bladder cancers occurring in transplant recipients.

Genes Linked to White-Tailed Jackrabbits' Winter Coat Color Change

Climate change, the researchers noted in Science, may lead to camouflage mismatch and increase predation of white-tailed jackrabbits.