Skip to main content
Premium Trial:

Request an Annual Quote

Your Experience, Your Genes

Some people insist that a place to eat is really good because that's what they've been told, even if their meal there wasn't very good, and that may be partly due to what version of the COMT gene, which is involved in dopamine transmission, those people have, reports Katherine Harmon at Scientific American. A new paper published online in The Journal of Neuroscience tested more than 70 people, using a computer-based program, to determine whether they rely on their own experiences or others' instructions to make their decisions. "People with an exceptional ability to spot inaccurate instructions and start making decisions using their own experience tended to have the Val/Val version of the gene, whereas those who needed 'greater confidence' that their experience was telling them to jettison earlier advice were more likely to have the Met allele," Harmon writes.

The Scan

Self-Reported Hearing Loss in Older Adults Begins Very Early in Life, Study Says

A JAMA Otolaryngology — Head & Neck Surgery study says polygenic risk scores associated with hearing loss in older adults is also associated with hearing decline in younger groups.

Genome-Wide Analysis Sheds Light on Genetics of ADHD

A genome-wide association study meta-analysis of attention-deficit hyperactivity disorder appearing in Nature Genetics links 76 genes to risk of having the disorder.

MicroRNA Cotargeting Linked to Lupus

A mouse-based study appearing in BMC Biology implicates two microRNAs with overlapping target sites in lupus.

Enzyme Involved in Lipid Metabolism Linked to Mutational Signatures

In Nature Genetics, a Wellcome Sanger Institute-led team found that APOBEC1 may contribute to the development of the SBS2 and SBS13 mutational signatures in the small intestine.