At Discovering Biology in a Digital World, Sandra Porter blogs about the excitement, adventure, and stomach-churning nerves that go along with starting a new company. Her startup aims "to develop instructional materials that help students and researchers use biological data," she writes, noting that a principal concern is getting people to pay for these materials.

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The UK's Nuffield Council on Bioethics says genetically modifying human embryos could be morally permissible, according to the Guardian.

A new Nature Biotechnology paper reports that CRISPR-Cas9 gene editing can lead to large deletions or complex rearrangements that could be pathogenic.

The Wall Street Journal likens a prototype developed by Synthetic Genomics to a "biological fax machine."

In PNAS this week: strategy for reactivating Rett syndrome-linked MECP2, small molecules able to suppress Staphylococcus aureus virulence, and more.