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You Give Us Three Links, We Give You Science

Today's edition of Science offers a couple of papers of particular interest to our community. The first comes from lead author Hun-Way Hwang of Johns Hopkins. Hwang's team demonstrates ($) that a specific human microRNA is driven by a snippet of sequence to localize to the nucleus.

In another paper, lead author Bo Huang from Stanford and crew report on a microfluidic chip ($) they designed to count fluorescently labeled proteins of low abundance in a single cell. Contents of the cell are separated by electrophoresis before being quantified by the fluorescence detection.

And in a letter cosigned by Mark Gerstein and Michael Seringhaus ($) of Yale University, the authors note that the 2006 Nobel Prize in Chemistry, like many others before it, celebrates the structural analysis of a biomolecule. "It would ... seem that the surest road to Stockholm is through a crystal tray," the authors conclude.

 

The Scan

Rise of BA.5

The New York Times reports that the Omicron subvariant BA.5 has become the dominant version of SARS-CoV-2 in the US.

UK Health Secretary Resigns

Sajid Javid, the UK health secretary, resigned along with Chancellor Rishi Sunak, saying they cannot work with Prime Minister Boris Johnson's government, CNN reports.

Clones From Freeze-Dried Cells

A team in Japan has cloned mice from freeze-dried skin cells, according to the Guardian.

Genome Research Papers on Craniosynostosis, Macaque Retrotransposition, More

In Genome Research this week: structural variants in craniosynostosis, LINE-1 activity in rhesus macaque brain, and more.