Today's edition of Science offers a couple of papers of particular interest to our community. The first comes from lead author Hun-Way Hwang of Johns Hopkins. Hwang's team demonstrates ($) that a specific human microRNA is driven by a snippet of sequence to localize to the nucleus. In another paper, lead author Bo Huang from Stanford and crew report on a microfluidic chip ($) they designed to count fluorescently labeled proteins of low abundance in a single cell. Contents of the cell are separated by electrophoresis before being quantified by the fluorescence detection. And in a letter cosigned by Mark Gerstein and Michael Seringhaus ($) of Yale University, the authors note that the 2006 Nobel Prize in Chemistry, like many others before it, celebrates the structural analysis of a biomolecule. "It would ... seem that the surest road to Stockholm is through a crystal tray," the authors conclude.
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