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Yes, But Can They Drink Beer Like People?

Mice are an important tool in biomedical research, particularly when it comes to testing possible new drugs, says 80beats' Joseph Castro. But when it comes to testing drug side effects, they're not always accurate — mouse livers and human livers react differently to pharmaceutical compounds. But in a new study published in PNAS, researchers at MIT say they've found a solution, Castro says: implanting mice with miniature, humanized livers. The team first developed tissue scaffolds by combining hepatocytes with other mouse and human cells. Once the scaffolds were implanted into the mice's abdominal cavities, the livers took about a week to integrate fully into the mice, Castro says. In addition to more accurately predicting drug toxicity, the researchers think the new livers will help scientists find treatments for diseases like hepatitis C, which mice don't normally contract, he adds.

The Scan

US Booster Eligibility Decision

The US CDC director recommends that people at high risk of developing COVID-19 due to their jobs also be eligible for COVID-19 boosters, in addition to those 65 years old and older or with underlying medical conditions.

Arizona Bill Before Judge

The Arizona Daily Star reports that a judge is weighing whether a new Arizona law restricting abortion due to genetic conditions is a ban or a restriction.

Additional Genes

Wales is rolling out new genetic testing service for cancer patients, according to BBC News.

Science Papers Examine State of Human Genomic Research, Single-Cell Protein Quantification

In Science this week: a number of editorials and policy reports discuss advances in human genomic research, and more.