To get your fill of Charles Darwin, listen to the Guardian's Science Weekly podcast. On the podcast with Alok Jha are Poet Laureate Ruth Padel, University College London's Steve Jones, and Cambridge University's Gillian Beer, to discusses Darwin's writings and what he read.

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Rare gene mutations are guiding the search for drugs to manage chronic pain without opioids, according to CNBC.

The new Francis Crick Institute building can get too noisy for some researchers to concentrate, according to the Guardian.

CBS News reports that there are still many vacancies at the White House Office of Science and Technology Policy, but that it's uncertain whether they will be filled.

In Nucleic Acids Research this week: pipeline to analyze and visualize bacterial genomes, database of global set of human genomes, and more.