At Genetic Future, blogger Daniel MacArthur warns readers who are thinking of buying a SNP scan from one of the three leading personal genomics companies to think twice. First, these tests gauge variation by looking at common variants, which misses the point:  disease isn't usually caused by simply one allelic mutation, but by many rare variants. Secondly, gene chips won't do the job here.

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The UK's Nuffield Council on Bioethics says genetically modifying human embryos could be morally permissible, according to the Guardian.

A new Nature Biotechnology paper reports that CRISPR-Cas9 gene editing can lead to large deletions or complex rearrangements that could be pathogenic.

The Wall Street Journal likens a prototype developed by Synthetic Genomics to a "biological fax machine."

In PNAS this week: strategy for reactivating Rett syndrome-linked MECP2, small molecules able to suppress Staphylococcus aureus virulence, and more.