Big Biotech may not spend as much on research and development as Big Pharma, but it manages to spend a pretty penny in the pursuit of new drugs and treatments, according to Fierce Biotech’s John Carroll. And when it comes to the "biggest spenders" in biotech, the US takes the cake, boasting 11 of the top 15 largest global companies in the field. The top five are all American, Carroll adds. Amgen was the top spender in 2010, with a budget of $2.72 billion. Biogen Idec takes second ($1.2 billion), Gilead third ($849 million), Genzyme is fourth ($805 million), and Celgene rounds off the top five ($745 million).