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Who's Up for the 10,000 Genomes Project?

At $50 million, the 1,000 Genomes Project is a steal, writes blogger Michael White at Adaptive Complexity. Not only will it make large amounts of genome sequence data available up front, the project will delve into more detailed SNP maps -- to more precisely map actual genetic variation to disease -- as well as structural variation, another major disease culprit that the HapMap doesn't cover. Finding rare variants is only possible, he writes, by sequencing huge numbers of genomes. "So it's obvious that 1,000 genomes is just a start."

The Scan

Another Resignation

According to the Wall Street Journal, a third advisory panel member has resigned following the US Food and Drug Administration's approval of an Alzheimer's disease drug.

Novavax Finds Its Vaccine Effective

Reuters reports Novavax's SARS-CoV-2 vaccine is more than 90 percent effective in preventing COVID-19.

Can't Be Used

The US Food and Drug Administration says millions of vaccine doses made at an embattled manufacturing facility cannot be used, the New York Times reports.

PLOS Papers on Frozen Shoulder GWAS, Epstein-Barr Effects on Immune Cell Epigenetics, More

In PLOS this week: genome-wide association study of frozen shoulder, epigenetic patterns of Epstein-Barr-infected B lymphocyte cells, and more.