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Whole-Genome Liability

As whole-genome sequencing becomes more common in the clinic, doctors may be facing the consequences of the technological shift, says this article at Slate from Future Tense's Gary Marchant and Rachel Lindor. Whole-genome sequencing opens up a number of liabilities for physicians, Marchant and Lindor say. For example, they write that even doctors who adopt whole-genome sequencing may face lawsuits if they do not recognize the significance of a variant or d not disclose medically relevant findings to patients' relatives. "Other dynamics of WGS will exacerbate these physician liability risks. There will be constant and rapid changes in our knowledge about the significance of various genetic variants, requiring doctors to constantly re-evaluate the diagnosis, prognosis, and treatment of their patients," Marchant and Lindor add.