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While in Humans, the Cost of Fitness Is Less Time for Internet Surfing

Over at his eponymous blog, Mike the Mad Biologist has a post suggesting that perhaps signal peptides are the fitness cost of antibiotic resistance in bacteria. Signal peptides, as he points out, have long been considered unimportant -- "for those of you who remember cassette tapes, signal peptides were thought to be like the white part at the beginning of the tape," he writes -- but his own work indicates that these peptides do indeed have a significant effect on protein function.

 

The Scan

Rise of BA.5

The New York Times reports that the Omicron subvariant BA.5 has become the dominant version of SARS-CoV-2 in the US.

UK Health Secretary Resigns

Sajid Javid, the UK health secretary, resigned along with Chancellor Rishi Sunak, saying they cannot work with Prime Minister Boris Johnson's government, CNN reports.

Clones From Freeze-Dried Cells

A team in Japan has cloned mice from freeze-dried skin cells, according to the Guardian.

Genome Research Papers on Craniosynostosis, Macaque Retrotransposition, More

In Genome Research this week: structural variants in craniosynostosis, LINE-1 activity in rhesus macaque brain, and more.