Jason Bobe blogs at The Personal Genome about an idea for a kind of open source application by which both experts and the general public could help to create a Richter scale for genome association study data. The scale would score each association with a number from 1 to 10, Bobe suggests, based on certain criteria such as penetrance, actionability, and validity. Scoring guidelines could include having more than one scale, transparency – as he puts it, "No secret sauce or private algorithms" – and utilizing existing resources to examine all this data.
Whew! That's an 8.2 on the Gene Association Scale
Aug 01, 2007