A the end of the year or decade, most lists are of the best or greatest achievements of that time frame, but Scientific American takes a different tack by listing the "Ten Science Letdowns of the New Millennium." Among those 10 include: a lack of victory in the war on cancer, the brain remaining mostly mysterious, and including evolution in science classrooms still being a topic of debate.

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Reuters reports that UK researchers are using gene-editing tools to develop flu-resistant chickens.

Nature calls for genomics to become part of the World Health Organization's cholera surveillance approach.

Vox explores a proposal to institute a lottery system to award grant funds.

In Genome Biology this week: gut microbiome study of individuals from Tanzania and Botswana, sixth version of the Network of Cancer Genes database, and more.