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A the end of the year or decade, most lists are of the best or greatest achievements of that time frame, but Scientific American takes a different tack by listing the "Ten Science Letdowns of the New Millennium." Among those 10 include: a lack of victory in the war on cancer, the brain remaining mostly mysterious, and including evolution in science classrooms still being a topic of debate.

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UK Royal Statistical Society is organizing a working group to develop guidelines for assessing COVID-19 tests, the Guardian reports.

The Washington Post reports that the White House chief of staff has asked the US Food and Drug Administration to justify the stricter standards it is seeking for a coronavirus vaccine.

President Donald Trump's "good genes" comment raises eugenics concerns, CNN reports.

In PLOS this week: genetic analysis of tremor condition, analysis of a West and Central African tree used in traditional medicine, and more.