A the end of the year or decade, most lists are of the best or greatest achievements of that time frame, but Scientific American takes a different tack by listing the "Ten Science Letdowns of the New Millennium." Among those 10 include: a lack of victory in the war on cancer, the brain remaining mostly mysterious, and including evolution in science classrooms still being a topic of debate.

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CNBC reports that Amazon invested in the startup Grail as it sees an opportunity for its cloud computing company in genomics.

Lawrence Krauss writes at Slate that science is needed for good public policy and should not be ignored.

Researchers are working on re-making the yeast genome from scratch, according to the Associated Press.

In Cell this week: functional profiling of Plasmodium genome, a self-inactivating rabies virus, and more.