At A Blog Around the Clock, the online community manager over at PLoS ONE tallies up the number of comments already posted to the first Journal Club discussion this fall, led by Jonathan Eisen. In just one week, there've been three ratings, each with a comment, one trackback, seven annotations, and four discussions spurring 14 more comments.

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The UK's Nuffield Council on Bioethics says genetically modifying human embryos could be morally permissible, according to the Guardian.

A new Nature Biotechnology paper reports that CRISPR-Cas9 gene editing can lead to large deletions or complex rearrangements that could be pathogenic.

The Wall Street Journal likens a prototype developed by Synthetic Genomics to a "biological fax machine."

In PNAS this week: strategy for reactivating Rett syndrome-linked MECP2, small molecules able to suppress Staphylococcus aureus virulence, and more.