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When GINA Just Isn't Enough

California Governor Jerry Brown signed a bill into law that extends the privacy and protections of the Genetic Information Nondiscrimination Act even further, says the University of Pennsylvania's Jennifer Wagner at Genomics Law Report. CalGINA, as it's called, amends existing non-discrimination laws in California to cover discrimination based on genetic information, Wagner says. "It mimics the federal Genetic Information Nondiscrimination Act in its definition of genetic information: genetic information does not include information about an individual's sex or age, but the definition does include genetic tests of an individual, genetic tests of an individual's family members and family medical history," she adds. But where the federal version of GINA says people are protected from genetic discrimination in the areas of employment and health insurance, CalGINA extends that to include receipt of emergency medical care, distribution of alcoholic club licenses, access to facilities, and participation in state-funded or state-administrated activity or programs, among others. "Ultimately, CalGINA amends the Business and Professions Code, the Education Code, the Elections Code, the Government Code, the Penal Code, the Revenue and Taxation Code, and the Welfare and Institutions Code," Wagner says.

The Scan

Single-Cell Sequencing Points to Embryo Mosaicism

Mosaicism may affect preimplantation genetic tests for aneuploidy, a single-cell sequencing-based analysis of almost three dozen embryos in PLOS Genetics finds.

Rett Syndrome Mouse Model Study Points to RNA Editing Possibilities

Investigators targeted MECP2 in mutant mouse models of Rett syndrome, showing in PNAS that they could restore its expression and dial down symptoms.

Investigators Find Shared, Distinct Genetic Contributors to Childhood Hodgkin Lymphoma

An association study in JAMA Network Open uncovers risk variants within and beyond the human leukocyte antigen locus.

Transcriptomic, Epigenetic Study Appears to Explain Anti-Viral Effects of TB Vaccine

Researchers report in Science Advances on an interferon signature and long-term shifts in monocyte cell DNA methylation in Bacille Calmette-Guérin-vaccinated infant samples.