Skip to main content
Premium Trial:

Request an Annual Quote

What's In the Cell Line?

Sometimes a cell line isn't what the researchers think it is.

As Retraction Watch reports, cell line contamination has led to the retraction of a 2012 PLOS One article that examined pathways involved in resistance to anoikis in adenoid cystic carcinoma. But, after a reader raised concerns with the journal, the study authors from Wuhan University submitted their lines for analysis, and that analysis revealed cross-contamination from HeLa cells in the ACC2 and ACCM lines they used.

"The authors have completed a short tandem repeat analysis on the cell lines and this has revealed cross-contamination with other human cells, which compromises the relevance of the work to human adenoid cystic carcinoma, and thus the conclusions of the study," the retraction notice says.

Retraction Watch notes that previous reports have found that somewhere between a fifth and a third of cancer cell lines tested have been contaminated.

The Scan

Not as High as Hoped

The Associated Press says initial results from a trial of CureVac's SARS-CoV-2 vaccine suggests low effectiveness in preventing COVID-19.

Finding Freshwater DNA

A new research project plans to use eDNA sampling to analyze freshwater rivers across the world, the Guardian reports.

Rise in Payments

Kaiser Health News investigates the rise of payments made by medical device companies to surgeons that could be in violation of anti-kickback laws.

Nature Papers Present Ginkgo Biloba Genome Assembly, Collection of Polygenic Indexes, More

In Nature this week: a nearly complete Ginkgo biloba genome assembly, polygenic indexes for dozens of phenotypes, and more.