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Big Science may be making headway according to scientists, but an article in US News and World Report disparages the whoppingly expensive Cancer Genome Project as only being a pilot that hasn't quite gotten off the ground due to flat funding and "cultural resistance to strategically directed big science." With a budget of $100 million, TCGA is "a costly effort even by genomics standards," writes Daniel MacArthur at Genetic Future.

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Researchers tie a variant in ADAMTS3 to breathing difficulties in dissimilar dog breeds, according to Discover's D-brief blog.

The Japan Times reports that researchers sequenced the genome of a woman who lived during the Jomon period.

Parents of children with rare genetic disease have to contend with shifts in the interpretation of genetic variants, the Wall Street Journal reports.

In Science this week: single-nucleus RNA sequencing of brain tissue from individuals with autism, and more.