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Highly-cited biomarker studies tend to report larger effect estimates for associations than subsequent meta-analyses do, says a literature review published in the Journal of the American Medical Association. John Ioannidis and Orestis Panagiotou combed through the ISI Web of Science to find studies that had been cited more than 400 times and had been published in a highly cited journal, and they searched for meta-analyses of those studies. From this, they evaluated 35 highly cited associations.

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The Wall Street Journal reports on gaps in COVID-19 testing affecting less affluent urban areas and rural locations.

According to NBC News, new SARS-CoV-2 variants are making it harder for researchers to model the course of the pandemic.

The New York Times reports that experts say President Joe Biden's goal of vaccinating 1 million people a day in the US in the next 100 days is too low a bar.

In Science this week: single-cell lineage tracing technique applied to study lung cancer metastasis, and more.