What a Result! Wait, a Second... | GenomeWeb

Highly-cited biomarker studies tend to report larger effect estimates for associations than subsequent meta-analyses do, says a literature review published in the Journal of the American Medical Association. John Ioannidis and Orestis Panagiotou combed through the ISI Web of Science to find studies that had been cited more than 400 times and had been published in a highly cited journal, and they searched for meta-analyses of those studies. From this, they evaluated 35 highly cited associations.

Get the full story

This story is free
for registered users

Registering provides access to this and other free content.

Register now.

Already have an account?
Login Now.

Related Posts

The Path Well Taken

This Week in PLOS

This Week in Nature

Define Your Terms

In Science this week: new single-cell RNA sequencing technique to study proliferating cells, and more.

South African researchers uncover bone cancer in an ancient hominin ancestor.

English bulldogs suffer from low genetic diversity and might have to be outbred to improve their health, according to a new study.

Theresa May tries to reassure researchers about the UK's commitment to science, New Scientist reports.