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What Happens When You Flip the Master Switch?

Feb 12, 2007

A team of researchers at Cold Spring Harbor Lab headed by Alea Mills found what they’ve shown to be a master switch for cancer. After performing studies on both mice and humans, Mills tracked the location of the so-far elusive granddaddy of tumor suppressor genes, CHD5. The CHD5 gene maps to a region on chromosome 1 and makes a protein that prevents cancer by turning on a tumor suppressive network. Their results have been published in the February issue of Cell.

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