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What Data Problem?

It's become a cliché, but the term "bottleneck" is an apt way to describe how data analysis gets held up after genomes are sequenced. A startup company thinks it has a way to smash the bottle, so to speak. California-based Bina Technologies has developed the "Bina Box," reports Technology Review's Susan Young — a machine connected to a cloud-hosted site for data management and analysis. "The group plans to sell [it] preloaded with software that can reduce the 300 gigabytes or so of raw data from a human genome into a few hundred megabytes of genetic information," Young says. "The box will upload the compressed dataset to Bina's cloud service for storage, sharing, and further analysis." The box works at speeds that are orders of magnitude faster than tools used at the Broad Institute, she adds. The company says it will works with a few genomics groups like Foundation Medicine to pilot test the technology, before it is made widely available.

The Scan

Two J&J Doses

Johnson & Johnson says two doses of its SARS-CoV-2 vaccine provides increased protection against symptomatic COVID-19, CNN reports.

Pfizer-BioNTech Vaccine Response in Kids

The Pfizer-BioNTech SARS-CoV-2 vaccine in a lower-dose format appears to generate an immune response among children, according to the Washington Post.

Chicken Changes to Prevent Disease

The Guardian writes that researchers are looking at gene editing chickens to help prevent future pandemics.

PNAS Papers on Siberian Dog Ancestry, Insect Reproduction, Hippocampal Neurogenesis

In PNAS this week: ancestry and admixture among Siberian dogs, hormone role in fruit fly reproduction, and more.