Skip to main content
Premium Trial:

Request an Annual Quote

What About Us, Wonder iPS Cells

A post at Science Progress hopes to remind everyone that even though stem cells are currently getting a bit of glory that iPS cells may eventually be a key tool. The post points to an article in last week's Cell in which Rudolf Jaenisch and his colleagues made iPS cells from Parkinson's disease patients' fibroblast cells that lacked viral factors and to another article in Nature from Andras Nagy's group that used transposons instead of viruses to reprogram the cells. It adds, though, that to make sure all the "kinks in the reprogramming process" are worked out, "we need to research human cells going all the way back to the embryonic stem stage."

The Scan

Octopus Brain Complexity Linked to MicroRNA Expansions

Investigators saw microRNA gene expansions coinciding with complex brains when they analyzed certain cephalopod transcriptomes, as they report in Science Advances.

Study Tracks Outcomes in Children Born to Zika Virus-Infected Mothers

By following pregnancy outcomes for women with RT-PCR-confirmed Zika virus infections, researchers saw in Lancet Regional Health congenital abnormalities in roughly one-third of live-born children.

Team Presents Benchmark Study of RNA Classification Tools

With more than 135 transcriptomic datasets, researchers tested two dozen coding and non-coding RNA classification tools, establishing a set of potentially misclassified transcripts, as they report in Nucleic Acids Research.

Breast Cancer Risk Related to Pathogenic BRCA1 Mutation May Be Modified by Repeats

Several variable number tandem repeats appear to impact breast cancer risk and age at diagnosis in almost 350 individuals carrying a risky Ashkenazi Jewish BRCA1 founder mutation.