We've All Been There

At Bitesize Bio, blogger Nick has had a bad week, leading him to post a list of 10 reasons not to be a scientist. Topping the list is ego, "Science attracts some straaaange people - and you have to work with them," he blogs. Nick also mentions the frustration of bench work, the repetition of the job, and the career structure of academia. Being a scientist has also hurt his Trivial Pursuit prowess.

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Microsoft co-founder Paul Allen also contributed to brain research, NPR reports.

The New York Times reports on the shifting interpretations of what some genetic variants mean over time.

MIT's Technology Review reports on Genentech's pursuit of personalized cancer vaccines.

In Cell this week: investigation of metastatic tumor evolution, more than 16,000 genetic variants introduced into the budding yeast model organism, and more.