This Week's Science

In this week’s Science, two Italian research groups reported on promising results from gene therapy clinical trials. In both studies, hematopoietic stem cells were removed from patients, then tranduced with lentiviral vectors encoding therapeutic genes and returned to the patients. For three children with the rare lysosomal storage disorder metachromatic leukodystrophy, which is caused by mutations in the ARSA gene, treatment appears to have halted progression of the disease.

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Researchers have sequenced the northern white rhinoceros to gauge whether it could be brought back from the edge of extinction, the New York Times reports.

Bavaria expands its forensic genetic analyses to include DNA phenotyping, raising discrimination concerns.

Tufts University researchers found a role for miRNA in transmitting stress between generations, the Economist reports.

In Science this week: gut microbiome influences liver cancer growth, spread; and more.