This Week's Science

In this week’s Science, two Italian research groups reported on promising results from gene therapy clinical trials. In both studies, hematopoietic stem cells were removed from patients, then tranduced with lentiviral vectors encoding therapeutic genes and returned to the patients. For three children with the rare lysosomal storage disorder metachromatic leukodystrophy, which is caused by mutations in the ARSA gene, treatment appears to have halted progression of the disease.

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NPR reports that with medical data being big business, some companies want to get patients involved.

The Asbury Park Press reports on the startup Genomic Prediction's test to determine an embryo's risk of disease.

In PNAS this week: optical mapping allows glimpse of structural variants, disease-linked GATA2 mutations boosts its protein activity, and more.

Senator Elizabeth Warren (D-Mass.) has released the results of a genetic ancestry analysis, the Boston Globe reports.