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This Week's Freebies in PNAS

A couple of open-access papers in the current issue of Proceedings of the National Academy of Sciences are particularly targeted for this community.

In a paper out of Ron Davis' lab at Stanford, the authors describe experiments using "a genome-wide assay for mapping introns in Saccharomyces cerevisiae" they developed with tiling arrays. The technique turned up previously undiscovered introns.

Another paper from the University of Lausanne reports on work from lead author Marta Fierro-Fernández and colleagues on their studies of supercoiling in bacterial DNA plasmids, from which the team posits that a particular topological effect "protects DNA molecules against extensive fork reversals," according to the abstract.


The Scan

Billions for Antivirals

The US is putting $3.2 billion toward a program to develop antivirals to treat COVID-19 in its early stages, the Wall Street Journal reports.

NFT of the Web

Tim Berners-Lee, who developed the World Wide Web, is auctioning its original source code as a non-fungible token, Reuters reports.

23andMe on the Nasdaq

23andMe's shares rose more than 20 percent following its merger with a special purpose acquisition company, as GenomeWeb has reported.

Science Papers Present GWAS of Brain Structure, System for Controlled Gene Transfer

In Science this week: genome-wide association study ties variants to white matter stricture in the brain, and more.