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This Week in PNAS

In early online publication, a collaboration between Northwestern University Feinberg School of Medicine, the University of Chicago, and Cold Spring Harbor Laboratory defined the transcriptome of human CD34+ hematopoietic stem-progenitor cells, finding that early hematopoiesis is an "orchestrated process" involving more than half the human genes distributed in various functions.

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Researchers tie a variant in ADAMTS3 to breathing difficulties in dissimilar dog breeds, according to Discover's D-brief blog.

The Japan Times reports that researchers sequenced the genome of a woman who lived during the Jomon period.

Parents of children with rare genetic disease have to contend with shifts in the interpretation of genetic variants, the Wall Street Journal reports.

In Science this week: single-nucleus RNA sequencing of brain tissue from individuals with autism, and more.