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This Week in Science: Jan 2, 2009

In a news focus, Science looks into the roles that science advisers have played in US administrations. How effective a science adviser is, the article says, depends on the relationship with the rest of the White House and with the scientific community. "It requires grace and intelligence and sharp elbows," Rodney Nichols, the former president of the New York Academy of Sciences, says.

Pacific Biosciences researchers say they have obtained single-molecule, real-time sequencing data by using DNA polymerase undergoing uninterrupted template-directed synthesis and four differentially, fluorescently-labeled deoxyribonucleoside triphosphates. They report a median accuracy rate of 99.3 percent.

The Scan

mRNA-Based Vaccine on the Way in China

China may soon have its own mRNA-based vaccine, according to Nature News.

Arranged Killing, Fraud Alleged by Prosecutors

The Wall Street Journal reports that prosecutors allege that the co-founder of a biotech arranged to have a business associate who threatened to expose him as a fraud killed.

Whirlwind Decade of CRISPR

The New York Times looks back at the 10 years since the University of California, Berkeley's Jennifer Doudna and her colleagues published their CRISPR paper.

PNAS Papers on Blue Cone Monochromacy Structural Variants, HIV-1 Mutant, T-ALL

In PNAS this week: structural variants linked to blue cone monochromacy, HIV-1 variants affecting the matrix protein p17, and more.