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This Week in Science: Apr 27, 2007

We've got microRNAs galore in today's edition of Science.

A paper from Rooij et al. at the University of Texas Southwestern Medical Center used a cardiac-specific microRNA to show that the MHC gene regulates heart growth and stress-related gene expression.

Meanwhile, a paper out of Caltech (Chen et al.) looks at selfish elements in the Drosophila genome that rely on microRNAs to silence a particular gene for embryogenesis.

These papers, from Thai et al. at Harvard Medical School and from Rodriguez, Vigorito, et al. at Sanger and the Babraham Institute, describe the importance of a conserved microRNA in the mammalian immune system.

And if microRNAs aren't your thing, Ishii and colleagues from Keio University report on high-throughput, systems-level studies of genetic and environmental perturbations in E. coli. A perspective for this paper was written by Uwe Sauer et al. on the importance of full system views of organisms.

 

The Scan

Alzheimer's Risk Gene Among Women

CNN reports that researchers have found that variants in MGMT contribute to Alzheimer's disease risk among women but not men.

Still Hanging Around

The Guardian writes that persistent pockets of SARS-CoV-2 in the body could contribute to long COVID.

Through a Little Spit

Enteric viruses like norovirus may also be transmitted through saliva, not just the fecal-oral route, according to New Scientist.

Nature Papers Present Method to Detect Full Transcriptome, Viruses Infecting Asgard Archaea, More

In Nature this week: VASA-seq approach to detect full transcriptome, analysis of viruses infecting Asgard archaea, and more.